The U.S. National Institutes of Health (NIH) maintains a database of past and present clinical trials. Your doctor can help decide whether a clinical trial could aid in your care. For a list of trials currently available, please go to Clinicaltrials.gov.
Some of the main factors researchers use when determining eligibility are:
- Age and gender of patient
- Overall health of patient
- Type and stage of mesothelioma
- Patient’s past treatment history
- Underlying medical conditions
Keytruda and CRS-207
Starting in June 2017 and running until 2019, six different cancer centers recruited patients for a phase II clinical trial. This involved two immunotherapy drugs: Keytruda (Pembrolizumab) and CRS-207. Researchers saw good results with both drugs in previous trials. Already FDA approved Keytruda, is a well-known immunotherapy medication for treating several types of cancer. Using Listeria bacteria, CRS-207 helps trigger an immune response to a specific tumor antigen.
In order to be for a patient to qualify for this trial, patients must already have received chemotherapy.
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