Nexium Users Have a 5 Times Greater Risk of Kidney Infection

Nexium (generic: esomeprazole) is a proton pump inhibitor (PPI), which is taken to relieve the symptoms of gastroesophageal reflux disorder (GERD), commonly referred to as acid reflux. PPIs, such as Nexium, work by blocking the release of stomach acid. It is supposed to temporarily coat the esophagus to prevent damage.

Nexium is not FDA-approved for long-term use, and studies confirm that 70% of PPI prescriptions should not have been made. It is one of the most overly prescribed drugs on the market. It is not a “healer” drug and should not be used for preventive care.

Study Links Nexium to Chronic Kidney Disease

Roughly, 15 million Americans use PPIs every year. Out of these, 20-50% are at a higher risk of chronic kidney disease compared with nonusers. The study published by JAMA Internal Medicine warned not to take Nexium at all or to use only for the shortest possible duration. Those that increased their dosage also increased their risk for kidney disease. Kidney disease occurs when the kidneys lose their ability to filter blood effectively. This can lead to end-stage renal failure, which is the need for life-long dialysis treatment or even a kidney transplant.

Nexium Linked to Acute Interstitial Nephritis

In 1992, it was first noted that PPIs cause Acute Interstitial Nephritis (AIN). Each new study described the 5 times greater risk users have in developing this deadly infection. AIN is a drug-induced bacterial infection of the kidneys. Nearly all cases of AIN are directly caused from taking PPIs like Nexium. The treatment is either drug removal, dialysis or a kidney transplant. However, PPIs have a high rebound rate. This means that when the drug is stopped most people have such a high dependency on it that they must continue to use it just to feel better. The cycle continues until patients end up on dialysis or death.

It was not until December 2014 that the FDA issued a new warning about the association between Nexium and kidney issues. This warning outlined the potential risk of developing acute interstitial nephritis, the sudden inflammation of the kidneys. The actual side effects for Nexium are much worse. The FDA neglected to warn consumers that Nexium users have a 50% risk of developing acute kidney injury, chronic kidney disease, and even kidney failure.


Nexium Other Side Effects

  • 15-20% increase risk of heart attack
  • Bone fractures with long term, high dose usage
  • Increased risk of dementia

Nexium vs Prilosec

Nexium and Prilosec are essentially the same drugs developed by AstraZeneca. When AstraZeneca feared the patent on Prilosec would lapse forcing them to lose billions in profits due to generic reproductions, they devised a plan to make Prilosec “new” again. The Prilosec molecules were split and mirrored thus making a “new” drug called Nexium. No studies confirm that Nexium is any different than Prilosec. It is still the same Prilosec just with a tweaked formula. The FDA even warned about marketing claims that Nexium was better than Prilosec since zero studies supported it.

AstraZeneca didn’t stop there to protect their lucrative patent. They claimed to be performing pediatric studies to receive six-month extensions.

Your Rights

When manufacturers produce unsafe products that create pain and suffering, you deserve compensation. Although no amount of money will change the fact that you have suffered a serious injury as a result of manufacturer irresponsibility, compensation will help offset your current and future medical costs, as well as provide for the pain and suffering you have experienced. By filing, you may also help protect others from needless distress.

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You may be eligible for compensation to ease the financial burdens associated with your injury. Contact us today to set up a free consultation, during which we will listen to your story, answer any questions you may have and discuss your legal rights and options. If you choose us to represent you, we will work with you on a contingency fee basis; this means you pay nothing until we have secured compensation for you, either through a jury verdict or settlement.

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